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Amoxicillin versus penicillin.

Amoxicillin versus penicillin

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amoxicillin vs penicillin
Ternatives to high-dose amoxicillin-clavulanate for treating AOM in these high-risk patients. In this double-blind, double-dummy multicenter clinical trial, we compared a novel, high-dose azithromycin regimen with high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent AOM. Three hundred four children were randomized; 300 received either high-dose azithromycin (20 mg kg of body weight once a day for 3 days) or high-dose amoxicillin-clavulanate (90 mg kg divided twice a day for 10 days). Tympanocentesis was performed at baseline; clinical response was assessed at day 12 to 16 and day 28 to 32. Two-thirds of patients were aged MATERIALS AND METHODS Top Abstract Introduction Materials and Methods Results Discussion References Study design and ethics. This was a randomized, double-blind, double-dummy trial involving 13 U.S. and 5 Latin American centers. The trial was conducted from March 2001 to March 2002. The design and conduct of the study were consistent with the 1998 Food and Drug Administration Guidance for Industry, Acute Otitis Media& 151;Developing Antimicrobial Drugs for Treatment (7). The Institutional Review Board or Independent Ethics Committee at each center approved the study protocol. Prior to enrollment, written informed consent was obtained from the parent or legal guardian of all participating patients. Patients. The study population consisted of children between 6 months and 6 years of age with a history of recurrent or persistent AOM, defined as follows: recurrent AOM, =" BORDER="0">1 episode within 30 days of enrollment, ="

| Penicillin overdose | How penicillin is made | Penicillin cat | Penicillin structure | Penicillin during pregnancy | Penicillin binding protein | Procaine penicillin |

[ Penicillin and breast feeding ]